Antihistamine Drug Shown to Stop Glioblastoma Tumor Growth in Mice
An antihistamine drug has been shown to halt the most aggressive form of brain cancer in mice, by triggering a cell death pathway without harming healthy cells. Glioblastoma – or…
Featured Biomedical Articles
Placental Stem Cells Regenerate Heart Tissue Following Heart Attack
Researchers at Mount Sinai Icahn School of Medicine have used a type of placental stem cell to successfully repair heart tissue following a heart attack in animal models. The research…
Researchers Identify Potential Metastatic Prostate Cancer Biomarker
Prostate cancer is one of the most common forms of cancer in men. Around 1 in 9 men will be diagnosed with the disease at some point in their lives….
Single Gene Deletion Halts Pancreatic Cancer in Mice
Researchers have halted pancreatic tumor formation in a mouse model that faithfully mimics the human disease by deleting a single gene and have identified three potential therapeutic targets for treating…
Researchers Identify ‘Anti-CRISPR’ Molecules that Inhibit Cas9 Enzyme Activity
One of the problems with the use of the CRISPR gene editing tool for treating genetic diseases in humans is how to control gene editing precisely once CRISPR-Cas9 has been…
ER+ Breast Cancer Cell Proliferation and Resistance Tamoxifen Linked to High Leucine Levels
Research conducted at Beth Israel Deaconess Medical Center (BIDMC) Cancer Center links resistance to the breast cancer drug Tamoxifen with high levels of the essential amino acid leucine. The research also…
Genes Involved in Stem Cell Proliferation Influenced by Biomaterials on Which they Are Grown
A variety of different substrates are used in the lab for growing stem cells. The substrates provide a surface on which stem cells adhere to. While some studies have suggested…
New Method Developed for Accurately Determining Off-Target CRISPR Edits
CRISPR has been hailed as one of the most promising methods of treating diseases, and while the gene editing technology has been shown to allow highly accurate edits to be…
Researchers 3D Bioprint Complete Heart from Patients Own Cells
Researchers at Tel Aviv University have 3D bioprinted a heart complete with atria, ventricles, and blood vessels using cells harvested from the patient. The work represents a major advance in…
First Human CRISPR Gene Editing Trial Commences in the United States
The first human CRISPR gene editing trial to be conducted in the United States has now commenced. The treatment is being given to two patients as part of a study…