Current In Vitro Model of Human Blood Brain Barrier is Flawed
The current model used to study the human blood brain barrier has been discovered to have a serious flaw: one which casts previous research using the model into question. The…
Biomedical Discoveries
Glioblastoma Linked to the Normal Brain Healing Process After Injury
New research suggests that following a brain injury, the healing process that sees new brain cells generated to replace damaged cells could make the development of glioblastoma more likely. Glioblastoma…
Decreased LEF1 Gene Activation Could Explain Lithium Resistance
Patients with bipolar disorder (BD) experience manic and depressive mood swings, which can be life threatening. While the symptoms can be managed with lithium, only a third of BD patients…
Biomarker for Aggressive Lymphoma Shows Which Patients Will Not Respond to Precision Therapy
Penn Medicine researchers have discovered a biomarker that identifies patients with aggressive activated B cell diffuse large B cell lymphoma (ABC-DLBCL) who will not respond to ibrutinib precision medicine therapy….
Brain Stem Cells Alerted by Inflammation Caused by Bacterial Infections
Brain stem cells are alerted by inflammation caused by bacterial infections in any part of the body and are prepared for activation, according to a new study conducted by researchers…
Treatment Prevents Heart Failure in Mice Following Myocardial Infarction
Researchers at the Baylor College of Medicine have developed a treatment that has proven to be effective in mice at preventing heart failure following a heart attack. When patients suffer…
Exosomes Show Potential for Accelerating Recovery from Ligament Injuries
Recovery from ligament injuries can be a long and painful process. Even with access to the best medical care, athletes can remain sidelined for many weeks or months and in…
New High Mortality Inflammatory Disorder Identified in Men
A team of NIH researchers have identified a new inflammatory disorder in men using a genotype-first strategy for disease discovery. The disorder, termed ‘vacuoles, E1 enzyme, X-linked, autoinflammatory and somatic…
Hunger Hormone Found to Play Key Role in Dementia in Parkinson’s Disease Patients
Researchers at the University of Swansea have discovered the gut hormone ghrelin is a key regulator of the formation of new nerve cells in the brain and have associated the…
New Targets Identified for the Treatment of Epilepsy
Epilepsy is a common neurological disease that causes seizures due to abnormal brain activity. The seizures can affect the whole brain or just one part, and can last for a…